Pharmaceutical Mergers on the Rise: Why Pfizer (PFE) Could Be a Smart Play

The pharmaceutical industry is seeing a wave of mergers and acquisitions (M&A) aimed at boosting growth amid rising challenges. With an industry-wide shift toward consolidation, companies are navigating expiring patents, heightened R&D costs, and pricing pressures. M&A allows companies to scale, optimize pipelines, and diversify revenue sources, and this environment has piqued interest among investors looking for companies with strong acquisition strategies. In this climate, Pfizer Inc. (PFE), with its notable M&A activity and robust pipeline, stands out as a potential winner.

Pfizer’s recent financials underscore its ability to adapt, as the company reported a substantial year-over-year revenue growth of 32% in Q3 2024, driven by both COVID-19 and non-COVID products. However, beyond immediate performance, Pfizer’s aggressive acquisitions and focus on high-growth areas signal a long-term strategy that could reward shareholders.

Industry Dynamics: What’s Driving Pharma Consolidation?

Several forces are propelling consolidation in the pharmaceutical sector, and these dynamics appear poised to continue shaping the market. Key drivers include:

Patent Expirations: As patents expire, revenue from major drugs can plummet. In response, companies seek acquisitions to backfill their pipelines with new drugs. Pfizer faces looming patent expirations on key products, making acquisitions a strategic necessity.

Rising R&D Costs: Costs of developing a new drug can exceed $2 billion, and the success rate is low. To mitigate costs and risks, pharma giants are buying innovative biotechs with promising pipelines instead of solely relying on in-house R&D. Pfizer’s acquisition of Seagen for its advanced oncology portfolio is a prime example of this trend.

Pipeline Diversification and Scale: From rare diseases to oncology, the pharma market’s fragmentation requires scale to reach different segments profitably. M&A enables companies to diversify across therapeutic areas, mitigating risk and stabilizing revenue. For Pfizer, its broadening oncology and rare disease portfolio reflects this approach.

Pfizer’s M&A Strategy: Building a High-Growth Pipeline

Pfizer has recently undertaken several acquisitions aimed at bolstering its drug portfolio and addressing therapeutic gaps. In December 2023, it acquired Seagen, gaining access to a lineup of oncology drugs, including promising assets in genitourinary and thoracic cancers. This acquisition aligns with Pfizer’s goal to become a top oncology player globally, which was echoed in its Q3 2024 earnings report, highlighting a 31% operational growth in oncology revenue.

Additionally, Pfizer has leveraged partnerships to advance its drug pipeline. Collaborations like those with BioNTech SE (NASDAQ:BNTX) for the COVID-19 vaccine underscore Pfizer’s agility in responding to market needs, an approach it could apply to its growing portfolio of anti-infectives and vaccines.

To sustain growth, Pfizer has also focused on high-demand fields, such as immunology, rare diseases, and oncology. With increased market share in prostate cancer treatment through XTANDI and new launches like PADCEV for bladder cancer, Pfizer has positioned itself for steady growth in high-margin markets.

Risks of Integration and Patent Expirations

While Pfizer’s acquisition strategy bolsters its growth outlook, there are challenges tied to integration and patent cliffs. Integrating a large acquisition, such as Seagen, can be costly and complex, especially as each acquired company brings its own operational nuances. Pfizer’s ongoing cost-cutting program, which aims to save at least $5.5 billion by 2027, will be essential to offset these integration costs and achieve synergies.

Moreover, Pfizer’s pipeline faces patent expirations over the coming decade, which could erode profits if replacements aren’t secured. Drugs like Ibrance and Eliquis, which have contributed substantially to revenue, are gradually facing generic competition. Pfizer’s response—through acquisitions, pipeline development, and partnerships—aims to counterbalance these expirations, but the effectiveness of this strategy will be critical.

Investment Recommendation: Is Pfizer a Buy?

Given the current M&A environment, Pfizer appears to be a well-positioned investment with a strategic focus on growth through acquisitions. Pfizer’s continued investment in oncology and other high-demand areas signals strong potential for future revenue gains, even as its COVID-19 products begin to decline. The company’s cost-saving initiatives, coupled with a raised revenue forecast for 2024 of $61–$64 billion, underscore management’s confidence in Pfizer’s growth trajectory despite external challenges.

Pfizer could be a “buy” for investors seeking exposure to a pharma company actively expanding its market share and pipeline through M&A. Given Pfizer’s focus on innovation, its expanding portfolio in oncology, and the robust performance of its newly acquired products, Pfizer represents a strong growth opportunity within the broader pharma sector’s consolidation wave. However, a “watch” position may be advisable for those cautious about integration risks and potential revenue pressures from patent expirations.

Pfizer’s Dividend Yield vs. Growth: Is It Time to Rebalance Your Portfolio?

Pfizer Inc. (PFE), striving to set the standard for quality, safety, and value in the discovery, development, and manufacture of biopharmaceutical products, reported solid second-quarter 2024 earnings and raised guidance for the full year. In the second quarter of 2024, the company’s revenues increased 2.1% year-over-year to $13.28 billion. This was PFE’s first quarter of top-line growth after reporting declines over the past five quarters.

Despite a modest year-over-year growth, Pfizer’s overall revenue growth has been sluggish, particularly in the post-pandemic period, as the pharma company lost the revenue boost from its COVID-19 vaccine. During the first six months of 2024, PFE’s revenues came in at $28.16 billion, down 11% year-over-year.

Furthermore, the company reported adjusted income and EPS of $3.40 billion and $0.60 for the second quarter, down 11.4% and 10.4% from the previous year’s quarter. While Pfizer’s adjusted EPS declined year-over-year, it surpassed analysts’ expectations of $0.46.

Dr. Albert Bourla, Chairman and CEO of Pfizer, said, “We are driving progress toward our 2024 strategic priorities through solid execution across the company. I am pleased with the strong performance of our product portfolio in the second quarter led by several of our acquired products, key in-line brands and recent commercial launches. Notably, we achieved exceptional growth in our Oncology portfolio, with strong revenue contribution from our legacy-Seagen products.”

“Overall, I am encouraged by our performance in the first half of 2024 and we remain focused on making a difference in the lives of patients as we continue to advance and strengthen our company,” Bourla added.

Following an improved second-quarter performance that exceeded past expectations, PFE raised its full-year guidance. The company increased its revenue guidance by $1 billion at the midpoint to a range of $59.5 to $62.5 billion. Its adjusted EPS is expected to be $2.45 to $2.65, up from the prior guidance of $2.15 to $2.35.

Pfizer’s Strength: A High Dividend Yield

Pfizer has raised dividends for 13 consecutive years. PFE pays an annual dividend of $0.42, which translates to a yield of 5.8%. The dividend yield of 5.80% is well above the average yield in the pharmaceutical sector. The company has demonstrated a long-standing commitment to returning capital to shareholders, having paid nearly $5 billion in dividends in the most recent quarter alone.

However, PFE’s dividend yield, while appealing, may not fully compensate for the company’s slower revenue growth trajectory. Since the pharmaceutical giant grapples with falling COVID-19 vaccine sales and patent cliffs on blockbuster drugs, future revenue growth may remain muted. This leaves Pfizer in a position where its high dividend yield could mask underlying financial challenges.

While Pfizer offers an attractive dividend yield, growth investors may find more attractive opportunities in faster-growing pharmaceutical companies like AbbVie Inc. (ABBV) and Eli Lilly and Company (LLY).

AbbVie: A Balance of Growth and Income

ABBV presents a compelling case for investors seeking both income and growth. The company boasts a strong product pipeline, particularly in immunology, oncology, neuroscience, and eye care, which positions it for sustained revenue growth. Moreover, AbbVie recently showcased the advancement of the solid tumor pipeline at ESMO 2024 with new data from its innovative antibody-drug conjugate (ADC) platform.

Further, in August 2024, the company completed the acquisition of Cerevel Therapeutics (CERE). This strategic acquisition strengthens its foundation in neuroscience and positions it to deliver sustainable long-term performance into the next decade and beyond.

For the second quarter that ended June 30, 2024, ABBV’s worldwide net revenues increased 4.3% year-over-year to $14.46 billion. Global net revenues from the oncology portfolio rose 10.5% year-over-year, and global net revenues from the neuroscience portfolio grew 14.7%.

“Our business continues to perform exceptionally well, with second quarter results meaningfully ahead of our expectations,” stated Robert A. Michael, chief executive officer of AbbVie. “Based upon the significant momentum of our ex-Humira growth platform, our continued investments in the business and our pipeline progress, we are very well positioned to deliver our top-tier long-term outlook.”

Following an outstanding second-quarter performance, AbbVie raised the 2024 adjusted EPS guidance range from $10.61-$10.81 to $10.71-$10.91.

In addition to these growth opportunities, AbbVie remains committed to rewarding shareholders. The company has a solid dividend track record, raising dividends for ten consecutive years. The company raised an annual dividend of $6.20, translating to a yield of 3.23% at the prevailing share price, making it an appealing option for investors who want a combination of dividend income and growth potential. Its balance of innovation and shareholder returns makes it an attractive long-term investment.

Should You Rebalance Your Portfolio?

For investors focused on maximizing long-term returns, it may be the right time to rebalance their portfolios. PFE’s high dividend yield remains attractive, but those seeking higher growth should consider trimming their positions and reallocating toward faster-growing pharmaceutical companies like ABBV or LLY.

5 Stocks to Buy Now in Response to Rising Unemployment Rate

The recently released August jobs report signaled a cooling down of the robust U.S. job market. With the strong job growth since last year acting as an Achilles heel for the Fed, the benchmark interest rate was raised several times to control inflation.

Although nonfarm payrolls beat estimates of 170,000 to arrive at 187,000 in August, the unemployment rate was 3.8%, rising sequentially to the highest since February 2022. Moreover, the real unemployment rate peaked at 7.1%, increasing by 0.4% and marking the highest since May 2022. Furthermore, the nonfarm payrolls for June and July were revised considerably downward.

The healthcare sector showed the most significant job gain, adding 71,000 jobs. The latest Job Opening and Labor Turnover Survey (JOLTS) report released last week showed that job openings fell to their lowest since March 2021, indicating softness in the labor market. The JOLTS report showed that there were 8.82 million jobs open at the end of July, a decline from the 9.16 million job openings in June.

Wells Fargo Economics senior economist Sarah House said, “Job openings per unemployed person remain above pre-pandemic levels, but this indicator is clearly on a downward trajectory amid cooling labor demand growth and impressive labor supply growth. A normalizing quit rate suggests that the fight over workers is subsiding, at least at the aggregate level.”

The Bureau of Economic Analysis (BEA) revealed that the real gross domestic product (GDP) rose at an annual rate of 2.1% in the second quarter. The latest estimate was lower than the initial advance estimate of a 2.4% growth.

Wells Fargo economist Shannon Seery said, “Overall, there were not any major revisions to the underlying GDP components compared to the first estimate of output, and today’s data do not materially change our overall view of the economy. Incoming data for Q3 show an economy that has continued to expand but with signs of some moderation. We continue to expect the economy to gradually slow during the second half of the year.”

Amid the rise in unemployment and an expected economic slowdown during the second half of the year, investors could consider investing in the healthcare sector as it is relatively stable compared to other sectors. The sector's inelastic demand enables companies in this space to maintain their profit margins irrespective of economic cycles.

Considering these factors, fundamentally strong healthcare stocks Eli Lilly and Company (LLY), Johnson & Johnson (JNJ), Merck & Co., Inc. (MRK), Pfizer Inc. (PFE), and Amgen Inc. (AMGN) could be solid portfolio additions now.

Let’s discuss the fundamentals of these stocks.

Eli Lilly and Company (LLY)

LLY discovers, develops, and markets human pharmaceuticals worldwide. It offers Basaglar, Humalog, Humalog Mix 75/25, Humalog U-200, Humalog Mix 50/50, insulin Iispro, insulin Iispro protamine, insulin Iispro mix 75/25, Humulin, Humulin 70/30, Humulin N, Humulin R, and Humulin U-500 for diabetes; and Jardiance, Trajenta, and Trulicity for type 2 diabetes.

On August 14, 2023, LLY announced the acquisition of Versanis Bio. The acquisition will expand LLY’s portfolio to include Versanis’ lead asset, bimagrumab, which is undergoing a Phase 2b study alone and in combination with semaglutide in adults living with overweight or obesity.

Ruth Gimeno, Ph.D., group vice president diabetes, obesity, and cardiometabolic research at LLY, said, “Combining our current incretin portfolio, including tirzepatide, with activin receptor blockers such as bimagrumab, could be the next major step in innovative treatments for those living with cardiometabolic diseases, like obesity.”

“The wealth of knowledge that our new colleagues from Versanis will bring to Lilly will propel our research and development efforts forward, ultimately benefiting patients around the world,” she added.

In terms of the trailing-12-month EBITDA margin, LLY’s 33.08% is 532.9% higher than the 5.23% industry average. Likewise, its 17.13% trailing-12-month levered FCF margin is significantly higher than the industry average of 0.22%. Furthermore, its 8.55% trailing-12-month Capex/Sales is 89.4% higher than the 4.52% industry average.

LLY’s revenue for the second quarter ended June 30, 2023, increased 28% year-over-year to $8.31 billion. The company’s non-GAAP gross margin increased 28% year-over-year to $6.63 billion. Its non-GAAP net income rose 68.3% over the prior-year quarter to $1.90 billion. Also, its non-GAAP EPS came in at $2.11, representing an increase of 68.8% year-over-year.

Analysts expect LLY’s EPS and revenue to increase 47% and 27.1% year-over-year to $2.91 and $8.82 billion, respectively. It surpassed the consensus EPS estimates in three of the trailing four quarters. Over the past year, the stock has gained 80.2%.

Johnson & Johnson (JNJ)

JNJ researches, develops, manufactures, and sells various products in the healthcare field worldwide. It operates under three segments: Consumer Health, Pharmaceutical, and MedTech.

On August 10, 2023, JNJ’s The Janssen Pharmaceutical Companies announced that the U.S. FDA had granted accelerated approval of TALVEY (talquetamab-tgvs), a first-in-class bispecific antibody for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 antibody.

In terms of trailing-12-month gross profit margin, JNJ’s 67.50% is 21.7% higher than the 55.44% industry average. Likewise, its 0.53x trailing-12-month asset turnover ratio is 41.1% higher than the industry average of 0.38x. Furthermore, the stock’s 21.99% trailing-12-month levered FCF margin is significantly higher than the 0.22% industry average.

For the second quarter ended June 30, 2023, JNJ’s reported sales rose 6.3% year-over-year to $25.53 billion. Its gross profit rose 7.6% year-over-year to $17.32 billion. The company’s adjusted net earnings increased 6.5% over the prior-year quarter to $7.36 billion. In addition, its adjusted EPS came in at $2.80, representing an increase of 8.1% year-over-year.

Street expects JNJ’s EPS for the quarter ending December 31, 2023, to increase 8.6% year-over-year to $2.55. Its fiscal 2024 revenue is expected to increase 3.8% year-over-year to $87.79 billion. It surpassed the Street EPS estimates in each of the trailing four quarters. Over the past six months, the stock has gained 5.2%.

Merck & Co., Inc. (MRK)

MRK is a global healthcare company that offers solutions through its prescription medicines, vaccines, biologic therapies, and animal health products. The company operates in the Pharmaceutical and Animal Health segments.

On June 16, 2023, MRK announced the completion of the acquisition of Prometheus Biosciences (RXDX). MRK’s Chairman and CEO Robert M. Davis said, “The Prometheus acquisition accelerates our growing presence in immunology, augments our diverse pipeline, and increases our ability to deliver patient value. This transaction is another example of Merck acting strategically and decisively when science and value align.”

In terms of trailing-12-month gross profit margin, MRK’s 73.22% is 32.1% higher than the 55.44% industry average. Likewise, the stock’s 7.28% trailing-12-month Capex/Sales is 61.3% higher than the 4.52% industry average. Furthermore, its 0.55x trailing-12-month asset turnover ratio is 46.9% higher than the industry average of 0.38x.

MRK’s sales for the second quarter ended June 30, 2023, increased 3% year-over-year to $15.04 billion. Its non-GAAP net loss that excludes certain items came in at $5.22 billion, compared to a non-GAAP net income of $4.74 billion in the year-ago quarter. Also, its non-GAAP loss per share came in at $2.06, compared to a non-GAAP EPS of $1.87 in the prior-year quarter.

For the quarter ending September 30, 2023, MRK’s EPS and revenue are expected to increase 4.7% and 1.8% year-over-year to $1.94 and $15.22 billion, respectively. It surpassed the consensus EPS estimates in each of the trailing four quarters. Over the past year, the stock has gained 26%.

Pfizer Inc. (PFE)

PFE discovers, develops, manufactures, markets, distributes, and sells biopharmaceutical products worldwide. It offers medicines and vaccines in various therapeutic areas, including cardiovascular metabolic and women's health, biosimilars, sterile injectable and anti-infective medicines, and oral COVID-19 treatment.

On August 21, 2023, PFE announced that the U.S. FDA approved ABRYSVO (Respiratory Syncytial Virus Vaccine), its bivalent RSV prefusion F (RSVpreF) vaccine, for the prevention of LRTD and severe LRTD caused by RSV in infants from birth up to six months of age by active immunization of pregnant individuals at 32 through 36 weeks gestational age.

PFE’s 32.53% trailing-12-month EBIT margin is significantly higher than the 0.15% industry average. Its 69.82% trailing-12-month gross profit margin is 25.9% higher than the industry average of 55.44%. Furthermore, the stock’s 15.85% trailing-12-month levered FCF margin is considerably higher than the industry average of 0.22%.  

PFE’s revenues for the second quarter ended June 30, 2023, declined 54% year-over-year to $12.73 billion. The company’s adjusted income decreased 67.1% year-over-year to $3.84 billion. Its adjusted EPS came in at $0.67, representing a decline of 67.2% over the prior-year quarter.  

PFE’s EPS and revenue for fiscal 2024 are expected to increase 3.9% and 0.1% year-over-year to $3.43 and $66.54 billion, respectively. It has an impressive earnings surprise history, surpassing its consensus EPS estimates in each of the trailing four quarters. Over the past month, the stock has gained 0.5%.  

Amgen Inc. (AMGN)

AMGN discovers, develops, manufactures, and delivers human therapeutics worldwide. It focuses on inflammation, oncology/hematology, bone health, cardiovascular disease, nephrology, and neuroscience.  

On September 1, 2023, AMGN and Horizon Therapeutics Public Limited Company (HZNP) announced the entry into a consent order agreement with the Federal Trade Commission (FTC), helping resolve the pending FTC administrative lawsuit. This effectively clears AMGN’s path to close the acquisition of HZNP.

With the consent order agreement, AMGN and HZNP expect that the parties will jointly file stipulated proposed orders to dismiss the preliminary injunction motion and dissolve the temporary restraining order in the U.S. District Court for the North District of Illinois. Both companies will seek the final approvals required under Irish law to close the acquisition.

In terms of the trailing-12-month gross profit margin, AMGN’s 74.29% is 34% higher than the 55.44% industry average. Likewise, its 37.82% trailing-12-month levered FCF margin is significantly higher than the industry average of 0.22%. Furthermore, its 51.78% trailing-12-month EBITDA margin is 890.5% higher than the 5.23% industry average.

For the fiscal second quarter ended June 30, 2023, AMGN’s total revenues increased 5.9% year-over-year to $6.99 billion. Its non-GAAP operating income rose 5.4% over the prior-year quarter to $3.52 billion. The company’s non-GAAP net income increased 7.5% year-over-year to $2.68 billion. Also, its non-GAAP EPS came in at $5, representing an increase of 7.5% year-over-year.

Street expects AMGN’s revenue for the quarter ending September 30, 2023, to increase 4% year-over-year to $6.92 billion. Its EPS for the quarter ending December 31, 2023, is expected to increase 15% year-over-year to $4.70. It surpassed the Street EPS estimates in three of the trailing four quarters. Over the past three months, the stock has gained 19.8%.

2 Overly Traded Stocks to Avoid This Fall

Stubborn inflation, rising interest rates, and consequent market volatility have kept many investors on edge. Inflation shows no signs of slowing, despite the Fed’s aggressive monetary policy tightening.

The consumer price index increased 0.4% sequentially in September, beating the Dow Jones estimate. The headline inflation was up 8.2% on a 12-month basis, hovering near the highest levels in decades.

The surging inflation and hot employment data for September strengthen the case for the Fed announcing a fourth 75-basis-point interest rate hike in next month’s meeting. Given these circumstances, the Conference Board sees a 96% chance of a recession in the United States over the coming 12 months, which might begin before the end of 2022. Moreover, the board projects 2022 real GDP to grow 1.5% year-over-year and 2023 growth to zero percent.

Since the economic headwinds are expected to keep the stock market under pressure, overly traded stock Pfizer Inc. (PFE) and Snap Inc. (SNAP) could be best avoided now, with their intermediate and long-term trends being down.

Pfizer Inc. (PFE)

Popular drugmaker PFE discovers, develops, manufactures, and distributes biopharmaceutical products worldwide. The pandemic made PFE one of the world’s most watched stocks, thanks to its COVID-19 drugs and vaccines. The stock has a market capitalization of $240.55 billion.

Although the company has recently announced some promising deals, acquisitions, and FDA approvals, the stock has declined 27.4% year-to-date, underperforming the S&P 500’s 23% decline. The stock has been underperforming the broader market, with investors pricing in the expected sales decline that the company might experience due to an anticipated slowdown in Covid vaccinations in the near term.

For the fiscal second quarter that ended June 30, 2022, PFE’s revenues increased 46.8% year-over-year to $27.74 billion. However, the company’s revenues largely leaned on sales of its Covid-19 vaccine Comirnaty and its antiviral treatment Paxlovid. The Covid-19 vaccine brought in $8.80 billion in revenue in the second quarter, while sales of Paxlovid totaled $8.10 billion.

Adjusted net income attributable to PFE common shareholders rose 93.5% from the year-ago value to $11.66 billion, while adjusted EPS grew 92.5% year-over-year to $2.04.

Wall Street analysts expect PFE’s revenues to decline in the about-to-be-reported quarter, which ended September 2022. The consensus revenue estimate of $21.33 billion for the fiscal third quarter indicates an 11.5% year-over-year decline. Continue reading "2 Overly Traded Stocks to Avoid This Fall"